While GLP-1 medications are highly effective for weight management, they are known to cause gastrointestinal side effects, especially during the dose titration phase.
Managing Nausea
Nausea is the most commonly reported side effect. It usually occurs in the 24-48 hours following an injection and tends to subside as your body adjusts to the medication.
- Eat smaller meals: Do not eat until you are completely full. Stop when you feel 70% full.
- Avoid high-fat foods: Fried foods and heavy creams take longer to digest and exacerbate nausea.
- Ginger: Ginger tea, chews, or supplements can naturally settle the stomach.
Combating Fatigue
Many users report feeling lethargic. This can be a direct effect of the medication, or an indirect effect of a severe caloric deficit.
To combat fatigue, ensure you are hitting your protein and calorie minimums. A deficit is required for weight loss, but starvation will destroy your energy levels. Prioritize sleep and gentle movement.
Digestive Changes
You may experience constipation due to the slowed gastric emptying.
Fiber is Your Friend
Aim for 25-30g of fiber daily. If you cannot get this from food alone, consider a daily psyllium husk supplement, taken with plenty of water.
Frequently Asked Questions
Do the side effects ever go away?
For the vast majority of users, side effects diminish significantly or disappear entirely once they have reached a maintenance dose and their body has adapted.
